Description

Mouse Anti-EBOV

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

4G7, monoclonal

species reactivity

Ebola virus, virus

packaging

antibody small pack of 25 μg

technique(s)

ELISA: suitable
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
neutralization: suitable

isotype

IgG2aκ

Specificity

Clone 4G7 is a mouse monoclonal antibody that detects envelope glycoprotein of Zaire Ebola virus. It binds to the C-terminal region of GP1.

Immunogen

Glycoprotein from Zaire Ebola virus, strain Mayinga, expressed in VSV G. Reverse genetics technique was used to create the recombinant virus VSV G/ZEBOV glycoprotein.

Application

Immunocytochemistry Analysis: A representative lot detected EBOV GP in Immunocytochemistry applications (Qiu, X., et. al. (2011). Clin Immunol. 141(2):218-27).

ELISA Analysis: Various dilutions of this antibody detected Envelope glycoprotein in Recombinant Ebola virus Glycoprotein minus the transmembrane region (EBOV rGP TM).

ELISA Analysis: A representative lot detected EBOV GP in ELISA applications (Qiu, X., et. al. (2011). Clin Immunol. 141(2):218-27).

Immunoprecipitation Analysis: A representative lot detected EBOV GP in Immunoprecipitation applications (Qiu, X., et. al. (2011). Clin Immunol. 141(2):218-27).

Neutralizing Analysis: A representative lot provided complete protection when administered prior to virus challenge. (Qiu, X., et. al. (2011). Clin Immunol. 141(2):218-27).

Anti-EBOV GP, clone 4G7, Cat. No. MABF2111, is a mouse monoclonal antibody that detects Envelope glycoprotein in Ebola virus and has been tested for use in ELISA, Immunocytochemistry, Immunoprecipitation, and Neutralizing applications.

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