Anti-Mouse IgG2a Antibody (GG2A-90A): A Powerful Tool for Mouse Immunoglobulin Detection

The Anti-Mouse IgG2a Antibody (GG2A-90A) is a highly specific research tool designed to detect and quantify the presence of IgG2a, a specific subclass of immunoglobulins (antibodies) produced by the mouse immune system. This antibody offers several advantages for researchers studying immune responses in mice.

Schematic diagram of mouse IgG2a-based Fab x sdAb-Fc BsAbs generated by using (A) controlled Fab-arm exchange (cFAE), (B) charge-pairs (CP) and (C) knobs-into-holes (KIH); (D) Design of bispecific control antibodies using the cFAE method.

 

Key Features:

Specificity: The GG2A-90A antibody is designed to bind specifically to the Fc region of mouse IgG2a molecules, minimizing cross-reactivity with other antibody subtypes or unrelated proteins. This ensures accurate and reliable detection of IgG2a in complex biological samples like serum or cell lysates.

Applications:  This antibody serves a variety of purposes in immunology research. It can be used in techniques such as ELISA (enzyme-linked immunosorbent assay) or Western blotting to quantify IgG2a levels, helping researchers understand the type and magnitude of the immune response in mice.

Conjugation Options:  The GG2A-90A antibody may be available in different conjugated forms, such as those linked to enzymes (e.g., horseradish peroxidase) or fluorescent molecules. These conjugates offer additional functionalities, like enabling signal amplification in ELISA or visualization of IgG2a in immunofluorescence microscopy.

Overall, the Anti-Mouse IgG2a Antibody (GG2A-90A) is a valuable tool for researchers investigating humoral immunity in mice. Its specificity, versatility, and potential for conjugation make it a powerful reagent for understanding the intricacies of the mouse immune response.

 

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